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Department of Biochemistry [ DST-FIST Sponsored Department ] 1.      Year of Establishment                            :           1985 2.      Brief history of the Department:                 In the department of Biochemistry the faculty members are actively engaged in teaching and research in chosen aspects of Biochemistry.  The areas of research interests are clinical biochemistry, enzymology, molecular biology, membrane biochemistry, plant molecular biology and chemistry of natural products.  The faculty members have successfully attracted research grants from various national and international funding agencies and established  independent laboratories. Chairmen, BOS & Head of Department Chairman/Chairperson Head/Coordinators Prof. K. Lakshmi Devii Dr.N.Ch. Varadacharyulu Syllabus Names and Designations of the faculty Chairman BOS: 255879 Head: 255761 Office: 255762 Name Designation Res. Off. 1. Dr. S. Dayananda Professor (On Lien) 2. Dr. D. Saralakumari Professor 278125 255761 3. Dr. K. Lakshmidevi Professor 276998 4. Dr. N. Ch. Varadacharyulu Professor 273337 5. Dr. Chitta Suresh Kumar Professor 255344 255644 Areas of specialization at M.Sc. level                               :           Nil Research level                       :      Molecular Biology, Clinical Biochemistry, Membrane Biochemistry, Bioinformatics, Drug Design.  Major Equipment in the Department:          Ultracentrifuge, UV-Visible spectorphotometer, High speed centrifuge, Cold room, Plant tissue culture room, PCR, DNA sequencing unit, Hybridisation chamber, Refrigerated shaking incubator, Networking facility, Ultracentrifuge, gel documentation ,Hybridization chamber, freezers, Spectrophotometers. Bioinforamtics Centre :(DST and UGC, New Delhi sponsored)           Class of art Bioinformtics Centre has been established in the department harboring Hi-end server (AMD athlon - uptron - dual processor), clinents of 15 (P-IV), HD scanner, networking with LINUX station, Vedio conferencing facility etc., Many Bioinformtics softwares (Molecular modeling, Drug design, Molecular Dynamics) were licenced to this Centre. Broad band connection will serve the internet facilities to this centre. Students from many universities have been working for their M.Sc. Project work specially on Predicting the stsructure of Durg targetted Proteins from bacterial pathogens. In addition S.K. University official web site (www.skuniversity.org) has been designed and maintained by this Bioinformtics Centre. Major Projects handled by the Department : Title of the project Funding agency Amount sanctioned Year of sanction Year of completion Ongoing/Completed Detection and characterization of OP-pesticide degrading  F. balustinum Plasmid mediated degradation of OP-Pesticides in F. balustinum: Cloning of opd gene and studies on its regulation Over expression of opd gene inS. lividans. Genetic analysis of OP-Pesticide degradation in F.balustinum. DST   DST DST Wellcome Trust 210000   2010000 1500000 4800000 1995   1996 1998 2001 1997   1999 2000 2003 Completed   Completed Completed Completed Biochemical Studies on Hypoglycemic action of  T. cardifolia. UGC 400000 1998 2001 Completed Isolation and genetic  characterisation of Organophosrus pesticide degrading bacteria isolated from agricultural soils of  Anantapur district, A.P. Development of Transgenic Plants for Insect Resistance through Genetic Engineering. Isolation, Purification and characterization of Phosphotriesterase – An Ecofriendly Pesticide degrading enzyme. Improvement of Ficus carica by Plant tissue culture techniques.   UGC   AICTE AICTE   UGC   20000   850000 700000   450000   1995   1998 1998   1999   1997   2000 2000   2001   Completed   Completed Completed   Completed Alcohol induced biochemical  adaptive changes in biomembranes. UGC 400000 1997 2000 Completed Homology modelling, Molecular docking and dynamics studies of D-alanine ligase enzyme of M. tuberculosis- A potential target for antitubeurculosis drug design UGC 984800 2008 2011 On-going
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